Non-syndromic retinitis pigmentosa , Ocular associations in Jordanian population

Abstract

Aims: This study aims to explore the spectrum of ocular associations and their frequency among a sample of Jordanian patients with non-syndromic retinitis pigmentosa, and to analyze the association of these complications with age and gender. Materials and methods: A total of fifty-nine patients with non-syndromic retinitis pigmentosa were selected from our data base at the Department of Ophthalmology, Jordan University Hospital, Amman from February 2017 to February 2018 to take part in this study. They underwent a comprehensive clinical evaluation in addition to corneal topography and retinal imaging with spectral domain optical coherence tomography. Results: Upon analyzing the relation between retinitis pigmentosa complications and both age and gender, we found that the mean age of patients with posterior subcapsular cataract was significantly (p< 0.001) higher than those without posterior subcapsular cataract (36.5 ±14.3 years and 24.7 ±8.9 years, respectively). All patients with subclinical cystoid macular edema (CMO) were males (6 patients comprising 16.7% of males). Conclusion: Posterior subcapsular cataract, CMO and posterior vitreous detachment (PVD) were the most common ocular association with non-syndromic retinitis pigmentosa. The older RP patients had a higher frequency of posterior subcapsular cataract, whereas male sex was associated with increased incidence of cystoid macular edema.